Electrophysiologic alterations seen in patients with advanced cardiac failure after angiotension converting enzyme inhibitor therapy
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چکیده
منابع مشابه
Angiotensin-converting enzyme inhibitor therapy improves respiratory muscle strength in patients with heart failure.
STUDY OBJECTIVES Respiratory muscle strength has been shown to be reduced in patients with chronic heart failure. The purpose of this prospective study was to determine whether long-term therapy with the angiotensin-converting enzyme (ACE) inhibitor perindopril improves respiratory muscle strength in patients with chronic heart failure. PATIENTS AND METHODS Eighteen patients with stable chron...
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Sir, Although angiotensin-converting enzyme (ACE) inhibitors are considered a milestone in the treatment of hypertension and microalbuminuria in diabetic patients w1,2x, some cau-tionary notes were reported in the setting of signi®cant reduction of renal function w3±5x. Discrepancy between long-term trials w1,2x and anecdotal reports w3±5x is probably due to the different selection of patients ...
متن کاملPrevention of nitrate tolerance with angiotension converting enzyme inhibitors.
BACKGROUND Activation of neurohumoral hormones or sulfhydryl group depletion may contribute to the development of nitroglycerin tolerance. In an attempt to prevent nitrate tolerance, this study evaluated the interaction of nitroglycerin with angiotensin converting enzyme (ACE) inhibitors with and without a sulfhydryl group. METHODS AND RESULTS Thirty-four subjects were randomized to a 7-day r...
متن کاملPrognostic importance of early worsening renal function after initiation of angiotensin-converting enzyme inhibitor therapy in patients with cardiac dysfunction.
BACKGROUND Worsening renal function (WRF) in the setting of heart failure has been associated with increased mortality. However, it is unclear if this decreased survival is a direct result of the reduction in glomerular filtration rate (GFR) or if the mechanism underlying the deterioration in GFR is driving prognosis. Given that WRF in the setting of angiotensin-converting enzyme inhibitor (ACE...
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BACKGROUND Recognizing that mechanical circulatory support with a left ventricular assist device (LVAD) induces changes in myocardial structure and contractile function, we examined whether there are changes in ventricular conduction and/or repolarization among failing human hearts after LVAD implantation. METHODS AND RESULTS We examined 12-lead electrocardiograms before surgery, immediately ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2003
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(03)81803-x